Particle mechanics approach to continuum constitutive modelling

Wear modelling: analytical, computational and mapping: a continuum mechanics approach

As a result of its widespread and pervasive economic consequences wear, the almost inevitable companion of friction, has been the subject of much scientific and empirical investigation; the literature is rich with ‘wear equations’ so that, on occasion, the practitioner can seem to have too much information rather than too little. Some guidance and reconciliation between analytical and computati...

A continuum approach to modelling cognitive disorders.

At the present time, the dominant conceptual framework in neuroscience views neurons as discrete information processing units. While this framework has undoubtedly been successful in explaining phenomena at the single-cell level, it has had less success in explaining large-scale neural phenomena such as cognitive disorders. An alternative conceptualization of brain function is in terms of an en...

Introduction to Continuum Mechanics

Modelling DNA loops using continuum and statistical mechanics.

The classical Kirchhoff elastic-rod model applied to DNA is extended to account for sequence-dependent intrinsic twist and curvature, anisotropic bending rigidity, electrostatic force interactions, and overdamped Brownian motion in a solvent. The zero-temperature equilibrium rod model is then applied to study the structural basis of the function of the lac repressor protein in the lac operon of...

Discrete Modelling and Discrete Algorithms in Continuum Mechanics